Cell-Penetrating Peptides(CPPs) and Drug Delivery

Interaction between Arg9s and a DOPC/DOPG membrane (preliminary)

Cell-Penetrating Peptides(CPPs) can deliver pharmalogically active molecules (e.g., proteins, plasmid-DNA, liposomes, and also nanoparticles) into cells, and thus they have great potential as future therapeutics. However, the uptake mechanisms are still debating. We have been working on several CPPs to identify their transport mechanisms and interactions with various types of lipid molecules.